Mammalian fertilization mechanisms
نویسندگان
چکیده
منابع مشابه
Mechanisms of Mammalian Sperm-Egg Interaction Leading to Fertilization
Mammalian fertilization, a species-specific event, is the net result of a highly orchestrated process that collectively results in the fusion of two radically different-looking haploid cells, sperm and egg, to form a diploid zygote, a cell with somatic chromosome numbers. Prior to the interaction of the opposite gametes, mammalian spermatozoa undergo many fascinating changes during development ...
متن کاملMammalian fertilization
fine,” says Waters. “But bustards have to be bill-fed.” After a period of quarantine in a special enclosure, they will eventually be released. The enclosure is open-topped to allow them to fly out to colonise surrounding fields. The immigrants have been taught to avoid both man and predators such as foxes using aversion therapy. Volunteers walk through the pen with dogs on leads, and if the bir...
متن کاملThe Molecules of Mammalian Fertilization
in some, ZP3 homologs are implicated as the key adhesion molecules, whereas in others, ZP2 homologs may play a dominant role (Topfer-Petersen et al., 1993). Although O-linked oligosaccharides on ZP3 are Dallas, Texas 75235 † Department of Cell Biology strongly implicated as being responsible for both sperm binding and signaling for the acrosome reaction, the University of Virginia Health Scienc...
متن کاملPervasive adaptive evolution in mammalian fertilization proteins.
Mammalian fertilization exhibits species specificity, and the proteins mediating sperm-egg interactions evolve rapidly between species. In this study, we demonstrate that the evolution of seven genes involved in mammalian fertilization is promoted by positive Darwinian selection by using likelihood ratio tests (LRTs). Several of these proteins are sperm proteins that have been implicated in bin...
متن کاملUnraveling the intricacies of mammalian fertilization
It is imperative to understand the molecular basis of various steps involved during fertilization. In the manuscript by Bianchi et al. a novel protein, Juno on egg membrane (oolemma) has been characterized that binds to sperm specific protein, Izumo-1. Monoclonal antibodies against Juno inhibited in vitro fertilization. Juno knock-out female mice failed to deliver litters on mating. It is rapid...
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ژورنال
عنوان ژورنال: Nature
سال: 1977
ISSN: 0028-0836,1476-4687
DOI: 10.1038/270084a0